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Introducing
Remend™ Eye Care

Available in two convenient presentations; Corneal Gel for dogs, cats and horses to aid in the management of superficial corneal ulcers, and Dry Eye Lubricant Drops for dogs, to provide long lasting moisture and lubrication to the eyes.

Hyaluronic Acid

The main component in Remend™ products is hyaluronic acid (HA), a non-immunogenic molecule found widely throughout human and animal tissues. Hyaluronic acid fulfils many biological functions including:

  • Promoting wound healing and helping to reduce scarring1
  • Cushioning and lubrication1
  • Maintaining tissue hydration1

The rapid degradation of naturally occurring HA in vivo has traditionally limited its clinical applications2. Through advanced technology it has become possible to chemically modify HA by cross linking the molecules. The cross-linked HA in Remend™ is more resistant to degradation2 and has several useful clinical applications.

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Remend™ Dry
Eye Lubricant Drops

Remend™ Dry Eye Lubricant Drops contain 0.4% hyaluronic acid. They provide long lasting lubrication to the eyes, allowing fewer applications than many of the currently available tear preparations4 aiding owner compliance.

In a study of 25 dogs with Keratoconjunctivitis sicca (KCS), Remend™ dry eye lubricant drops were applied topically to the eyes twice daily, and clinical signs associated with the condition (hyperaemia, irritation and ocular discharge) were assessed before and after treatment.

  • Remend™ significantly improved the characteristic signs of canine KCS in two weeks when given twice daily, a reduced dosing schedule compared to many other tear supplements3
  • This reduced dosing regimen may encourage owner compliance as an aid to the management of Dry Eye

Remend™ should be used as an adjunctive therapy alongside prescription medications in the management of KCS.

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Remend™
Corneal Gel

Remend™ Corneal Gel is indicated for use as an aid to healing in superficial corneal ulcers in dogs, cats and horses. In order for superficial corneal ulcers to heal, it is necessary for cells to migrate from the edges of the defect, and re-epithelialise the area that has been lost.

The cross-linked HA in Remend™ Corneal Gel provides an environment that facilitates cell migration, making it a valuable aid to the healing process.2

Remend™ is not intended for use in stromal ulcers or melting ulcers and does not replace the need for debridement in indolent ulcers. Remend™ does not contain an antibiotic; where antimicrobial treatment is required, appropriate therapy should be initiated.

KCS Report

in partnership with Chris Dixon BVSc CertVOphthal MRCVS

This guide provides a concise overview of KCS including aetiology, diagnosis, treatment and ongoing management. It also answers some commonly asked questions around how to manage refractory cases and when to refer.

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Vet Training Videos

in partnership with Chris Dixon BVSc CertVOphthal MRCVS

Join Chris Dixon, ophthalmologist at Veterinary Vision Ophthalmic referrals in this ‘back to basics’ bite-sized revision video series, focusing on the canine ophthalmic examination and tips on diagnosis and the management of common ocular conditions.

Performing an
external ophthalmic
examination.

In this video Chris explores how to perform an external ocular examination, and demonstrates some key ocular reflex and response tests, including the menace response, dazzle reflex, and pupillary light reflex.

Effective use of the ophthalmoscope and examining the fundus

In this video Chris covers practical advice on how to perform an ocular examination; including tips on how to use an ophthalmoscope effectively and examining the internal ocular structures including distant direct examination, indirect examination and close direct examination.

Examining
the cornea
and KCS

In the final video Chris includes practical advice and tips on how to perform an examination of the cornea, assessing for corneal ulceration, how to perform a Schirmer tear test, diagnosing and treating dogs with Keratoconjunctivitis sicca (KCS) and optimal use of artificial lubrication.

Waiting Room Videos

in partnership with Paul Manktelow BVMS MRCVS

Join TV vet Paul Manktelow in this three part, fully subtitled educational video series ‘The world through their eyes’ to help educate your clients on canine ocular health. These videos are ideal for use in the practice waiting room.

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How your dog sees the world – Vision Matters

Paul discusses how a dog’s eyes work and gives a fascinating insight into how they see the world.

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Caring for your dog’s eyes – Vision Matters

Paul helps pet owners assess their dog’s eyes more thoroughly to help them identify problems early and talks about the most common ocular conditions, such as corneal ulcers.

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Does your dog have Dry Eye? – Vision Matters

In this video Paul looks at what symptoms to look out for when owners are concerned about Dry Eye, how it is diagnosed and the treatment of this common disease.

Vet FAQs

How often does Remend™ need to be applied?

Remend™ Corneal Gel can be applied twice daily to aid in the management of superficial corneal ulcers.

Remend™ Dry Eye lubricant yields excellent results with just twice daily application, but can be applied up to four times daily if required.

Do I need to use an antibiotic with Remend™?

Remend™ does not contain an antimicrobial, so if infection is a risk or is suspected, appropriate therapy should be initiated alongside Remend™. Remend™ should follow the application of other topical medications, and at least 5 minutes should be left between the application of Remend™ and other products.

Can I use Corneal Gel to treat Dye Eye instead of Dry Eye Lubricant and vice versa?

The concentration of cross linked HA and the consistency of each presentation has been specifically formulated for the therapeutic area indicated, and alternative use will not yield optimal results.

How long will Remend™ last once it has been opened?

There is no preservative in Remend™ and this should be borne in mind with relation to the shelf life. It is advised that a bottle is disposed of one month after opening.

Can I use Remend™ in place of Optimmune®?

Remend™ is intended to be used alongside licensed medications such as Optimmune®. It does not slow down the progressive immune destruction of the lacrimal glands as is the licensed indication of Optimmune®. In many cases of KCS gland destruction is advanced by the time of diagnosis, so therapy slowing down the destruction of the lacrimal glands may be less effective5, and provision of drops that hydrate and lubricate the eye surface will also be required.

Even in dogs that respond well to treatment with cyclosporine, additional tear supplementation is still recommended as this helps keep the eyes as comfortable and pain-free as possible. One of the limitations of many of the tear supplements currently available is the need for very frequent administration (often four to six times daily). This can be a barrier to owner compliance whereas with the unique structure of Remend™ application only needs to be twice daily.6

How is Bayer supporting Dry Eye Awareness during the month of July?

We are excited to support the Dry Eye Awareness Month initiative in practice and have created a special promotional pack to help you. This includes:

  • Educational wall display for the waiting room or consult room
  • A copy of Chris Dixon’s KCS report
  • Client leaflets
  • Pug Mug
  • Promotional ‘pug bugs’
  • Balloons

Please speak to your Bayer Territory Manager to find out how to order your promotional pack or email ah.marketing@bayer.com

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Get More Practice Materials

If you wish to order additional client leaflets or promotional materials for Remend™, or any other Bayer materials please join us on the Bayer Vet Centre.

Bayer Vet Centre

Welcome to our dedicated website for Animal health professionals. Once you have set up your account you can participate in free online CPD, learn about products and order your practice marketing materials. We also host a suite of business development resources and provide regular updates on news and events.

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References: 1.Chen JWY, Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair and Regeneration 1999; 7:79-89. 2.Yang G, Espandar L, Mamalis N, Prestwich GD. A cross-linked hyaluronan gel accelerates healing of corneal epithelial abrasion and alkali burn injuries in rabbits. Vet Ophthalmol. 2010;13(3) :144–150. 3.Williams D, Mann B. A Crosslinked HA-Based Hydrogel Ameliorates Dry Eye Symptoms in Dogs. International Journal of Biomaterials. Volume 2013, Article ID 460437 4. Williams D, Middleton S, Fattahian H, Moridpour R. Comparison of hyaluronic acid-containing topical eye drops with carbomer-based topical ocular gel as a tear replacement in canine keratoconjunctivitis sicca: A prospective study in twenty five dogs. Veterinary Research Forum. 2012; 3(4): 229-232. 5. Hadzi Milic M, Dordevic J, Krstic N. Cyclosporine A (CsA) treatment of chronic autoimmune-mediated keratoconjunctivitis sicca in dogs. Acta Veterinaria (Beograd). 2013; 5-6(63): 677-685.6. 6. Williams D, Mann B. A crosslinked HA based hydrogel ameliorates Dry Eye symptoms in dogs. International Journal of biomaterials Volume 2013 Article ID 460437

References: 1.Chen JWY, Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair and Regeneration 1999; 7:79-89. 2.Williams D, Mann B. A Crosslinked HA-Based Hydrogel Ameliorates Dry Eye Symptoms in Dogs. International Journal of Biomaterials. Volume 2013, Article ID 460437 3.Yang G, Espandar L, Mamalis N, Prestwich GD. A cross-linked hyaluronan gel accelerates healing of corneal epithelial abrasion and alkali burn injuries in rabbits. Vet Ophthalmol. 2010;13(3) :144–150. 4. Hadzi Milic M, Dordevic J, Krstic N. Cyclosporine A (CsA) treatment of chronic autoimmune-mediated keratoconjunctivitis sicca in dogs. Acta Veterinaria (Beograd). 2013; 5-6(63): 677-685.6. 5. Williams D, Mann B. A crosslinked HA based hydrogel ameliorates Dry Eye symptoms in dogs. International Journal of biomaterials Volume 2013 Article ID 460437

Use Medicines Responsibly (www.noah.co.uk/responsible) 
Remend™ Dry Eye Lubricant Drops contain water, Hyaasent-STM, sodium chloride, disodium phosphate, potassium chloride and potassium phosphate. Further information is available from the pack insert, at www.remend.co.uk, or on request. For more information relating to other products mentioned in this report, please refer to the appropriate data sheet at noahcompendium.co.uk Bayer plc, 400 South Oak Way, Green Park, Reading, Berkshire, RG2 6AD. Tel: 0118 206 3000.